The ability of synthetic zeolites to encapsulate and deliver the bioactive compound curcumin, which is well-known for its therapeutic effects, is investigated. Curcumin, the active ingredient of turmeric, is a water-insoluble compound that has attracted great attention in recent years because of its anti-inflammatory properties and anticancer activity. In our research, we use different types of zeolites (LTA and FAU) for loading of curcumin. The structural properties and morphology of the zeolite-based carriers, before and after curcumin loading, were investigated using scanning electron microscopy, X-ray diffraction, and differential scanning calorimetry. UV-Vis absorption spectra were collected to quantify the loading capacity. Results are useful to assess the potential of synthetic zeolites for curcumin delivery in therapeutic applications.
SYNTHETIC ZEOLITES AND ENCAPSULATION OF BIOACTIVE CURCUMIN FOR DRUG DELIVERY APPLICATIONS / Ahaliabadeh, Zahra; Saviano, Giovanna; Santonicola, Mariagabriella. - (2019). (Intervento presentato al convegno 4th Euro Asia Zeolite Conference tenutosi a Taormina, Italy).
SYNTHETIC ZEOLITES AND ENCAPSULATION OF BIOACTIVE CURCUMIN FOR DRUG DELIVERY APPLICATIONS
Zahra AhaliAbadeh;Giovanna Saviano;MariaGabriella Santonicola
2019
Abstract
The ability of synthetic zeolites to encapsulate and deliver the bioactive compound curcumin, which is well-known for its therapeutic effects, is investigated. Curcumin, the active ingredient of turmeric, is a water-insoluble compound that has attracted great attention in recent years because of its anti-inflammatory properties and anticancer activity. In our research, we use different types of zeolites (LTA and FAU) for loading of curcumin. The structural properties and morphology of the zeolite-based carriers, before and after curcumin loading, were investigated using scanning electron microscopy, X-ray diffraction, and differential scanning calorimetry. UV-Vis absorption spectra were collected to quantify the loading capacity. Results are useful to assess the potential of synthetic zeolites for curcumin delivery in therapeutic applications.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.